An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell lines.

The VAI RNA of adenovirus is a small, RNA polymerase III-transcribed species required for the efficient translation of host cell and viral mRNAs late after infection. VAI RNA prevented activation of the interferon-induced P1/eIF-2 alpha kinase. In its absence the kinase was activated, eIF-2 alpha wa...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Kitajewski, J, Schneider, R J, Safer, B, Shenk, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3796608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.12.4493-4498.1986
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