An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell lines.
The VAI RNA of adenovirus is a small, RNA polymerase III-transcribed species required for the efficient translation of host cell and viral mRNAs late after infection. VAI RNA prevented activation of the interferon-induced P1/eIF-2 alpha kinase. In its absence the kinase was activated, eIF-2 alpha wa...
में बचाया:
| में प्रकाशित: | Mol Cell Biol |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Taylor & Francis
1986
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC367233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3796608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.6.12.4493-4498.1986 |
| टैग: |
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