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Thymic epithelial cells use macroautophagy to turn their inside out for CD4 T cell tolerance
During development in the thymus, each T lymphocyte is equipped with one, essentially unique, T cell receptor (TCR)-specificity. Due to its random nature, this process inevitably also leads to the emergence of potentially dangerous T lymphocytes that may recognize ‘self.’ Nevertheless, autoimmune ti...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672305/ https://ncbi.nlm.nih.gov/pubmed/23548947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24374 |
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