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CD4 T Cell Tolerance to Human C-reactive Protein, an Inducible Serum Protein, Is Mediated by Medullary Thymic Epithelium

Inducible serum proteins whose concentrations oscillate between nontolerogenic and tolerogenic levels pose a particular challenge to the maintenance of self-tolerance. Temporal restrictions of intrathymic antigen supply should prevent continuous central tolerization of T cells, in analogy to the spa...

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Bibliografski detalji
Glavni autori: Klein, Ludger, Klein, Thomas, Rüther, Ulrich, Kyewski, Bruno
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525550/
https://ncbi.nlm.nih.gov/pubmed/9653079
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