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PIK3C3/VPS34, the class III PtdIns 3-kinase, plays indispensable roles in the podocyte

The mammalian homolog of yeast Vps34 (PIK3C3/VPS34) is implicated in the regulation of autophagy, and recent studies have suggested that autophagy is a key mechanism in maintaining the integrity of renal glomerular podocytes. To date, however, the role of PIK3C3 in podocytes has remained unknown. We...

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Библиографические подробности
Главный автор: Chen, Jian-Kang
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672302/
https://ncbi.nlm.nih.gov/pubmed/23518611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24230
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