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Intermolecular domain docking in the hairpin ribozyme: Metal dependence, binding kinetics and catalysis
The hairpin ribozyme is a prototype small, self-cleaving RNA motif. It exists naturally as a four-way RNA junction containing two internal loops on adjoining arms. These two loops interact in a cation-driven docking step prior to chemical catalysis to form a tightly integrated structure, with dramat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672286/ https://ncbi.nlm.nih.gov/pubmed/23324606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23609 |
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