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Protective Effects of Andrographolide Analogue AL-1 on ROS-Induced RIN-mβ Cell Death by Inducing ROS Generation

Oxidative stress is considered to be a major factor contributing to pathogenesis and progression of many diseases. A novel andrographolide-lipoic acid conjugate (AL-1) could protect pancreatic β-cells from reactive oxygen species (ROS)-induced oxidative injury. However, its protective mechanism is s...

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Detalhes bibliográficos
Main Authors: Yan, Guang-Rong, Zhou, Hui-Hua, Wang, Yang, Zhong, Yin, Tan, Zi-Lu, Wang, Yuqiang, He, Qing-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672203/
https://ncbi.nlm.nih.gov/pubmed/23750203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063656
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