Epigenetic therapy in allogeneic hematopoietic stem cell transplantation

DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decit...

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Bibliographic Details
Main Authors: Bashir, Qaiser, William, Basem Magdy, Garcia-Manero, Guillermo, de Lima, Marcos
Format: Artigo
Language:Inglês
Published: Associação Brasileira de Hematologia e Hemoterapia 2013
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672123/
https://ncbi.nlm.nih.gov/pubmed/23741191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20130034
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