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Epigenetic therapy in allogeneic hematopoietic stem cell transplantation

DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decit...

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Detalhes bibliográficos
Main Authors: Bashir, Qaiser, William, Basem Magdy, Garcia-Manero, Guillermo, de Lima, Marcos
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Hematologia e Hemoterapia 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672123/
https://ncbi.nlm.nih.gov/pubmed/23741191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5581/1516-8484.20130034
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