Loading...

SIRT1 Is a Circadian Deacetylase for Core Clock Components

The transcriptional activator CLOCK is a histone acetyltransferase that is required for the circadian expression of many genes. Asher et al. (2008) and Nakahata et al. (2008) now demonstrate that the NAD(+)-dependent enzyme SIRT1 functions as a histone deacetylase that counteracts the activity of CL...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Belden, William J., Dunlap, Jay C.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671948/
https://ncbi.nlm.nih.gov/pubmed/18662537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.07.010
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!