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The Effect of Desulfation of Chondroitin Sulfate on Interactions with Positively Charged Growth Factors and Upregulation of Cartilaginous Markers in Encapsulated MSCs

Sulfated glycosaminoglycans (GAGs) are known to interact electrostatically with positively charged growth factors to modulate signaling. Therefore, regulating the degree of sulfation of GAGs may be a promising approach to tailor biomaterial carriers for controlled growth factor delivery and release....

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Autores principales: Lim, Jeremy J., Temenoff, Johnna S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671883/
https://ncbi.nlm.nih.gov/pubmed/23570717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.03.037
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