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Mitochondrial DNA Oxidative Damage and Repair in Aging and Alzheimer's Disease

Significance: Mitochondria are fundamental to the life and proper functioning of cells. These organelles play a key role in energy production, in maintaining homeostatic levels of second messengers (e.g., reactive oxygen species and calcium), and in the coordination of apoptotic cell death. The role...

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Detalhes bibliográficos
Main Authors: Santos, Renato X., Correia, Sónia C., Zhu, Xiongwei, Smith, Mark A., Moreira, Paula I., Castellani, Rudy J., Nunomura, Akihiko, Perry, George
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671662/
https://ncbi.nlm.nih.gov/pubmed/23216311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.5039
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