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The LIM Protein Ajuba Restricts the Second Heart Field Progenitor Pool by Regulating Isl1 Activity

Morphogenesis of the heart requires tight control of cardiac progenitor cell specification, expansion, and differentiation. Retinoic acid (RA) signaling restricts expansion of the second heart field (SHF), serving as an important morphogen in heart development. Here, we identify the LIM domain prote...

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Detalhes bibliográficos
Main Authors: Witzel, Hagen R., Jungblut, Benno, Choe, Chong Pyo, Crump, J. Gage, Braun, Thomas, Dobreva, Gergana
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671491/
https://ncbi.nlm.nih.gov/pubmed/22771034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.06.005
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