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Atherogenesis May Involve the Prooxidant and Proinflammatory Effects of Ferryl Hemoglobin
Oxidized cell-free hemoglobin (Hb), including covalently cross-linked Hb multimers, is present in advanced atherosclerotic lesions. Oxidation of Hb produces methemoglobin (Fe(3+)) and ferryl hemoglobin (Fe(4+) = O(2−)). Ferryl iron is unstable and can return to the Fe(3+) state by reacting with spec...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Hindawi Publishing Corporation
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671302/ https://ncbi.nlm.nih.gov/pubmed/23766856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/676425 |
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