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Sites of strong Rec12/Spo11 binding in the fission yeast genome are associated with meiotic recombination and with centromeres

Meiotic recombination arises from Rec12/Spo11-dependent formation of DNA double-strand breaks (DSBs) and their subsequent repair. We identified Rec12-binding peaks across the S. pombe genome using chromatin immunoprecipitation after reversible formaldehyde cross-linking combined with whole-genome DN...

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Autors principals: Ludin, Katja, Mata, Juan, Watt, Stephen, Lehmann, Elisabeth, Bähler, Jürg, Kohli, Jürg
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671157/
https://ncbi.nlm.nih.gov/pubmed/18449558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-008-0159-3
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