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CD47 is required for suppression of allograft rejection by donor specific transfusion()
CD47 is a ligand of an inhibitory receptor, signal regulatory protein (SIRP)α, and its interaction with SIRPα on macrophages prevents phagocytosis of autologous hematopoietic cells. CD47-SIRPα signaling also regulates dendritic cell (DC) endocytosis, activation and maturation. Here we show that CD47...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670954/ https://ncbi.nlm.nih.gov/pubmed/20208011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901550 |
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