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Developmentally-regulated subnuclear genome reorganization restricts neural progenitor competence in Drosophila
Stem/progenitor cells often generate distinct cell types in a stereotyped birth order, and over time lose competence to specify earlier-born fates by unknown mechanisms. In Drosophila, the Hunchback transcription factor acts in neural progenitors (neuroblasts) to specify early-born neurons, in part...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670710/ https://ncbi.nlm.nih.gov/pubmed/23332748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.049 |
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