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The Cells and Circuitry for Itch Responses in Mice

Itch is triggered by somatosensory neurons expressing the ion-channel TRPV1 but the mechanisms underlying this nociceptive response remain poorly understood. Here we showed that the neuropeptide, Nppb, is expressed in a subset of TRPV1-neurons and found that Nppb(−/−) mice selectively lose almost al...

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Detalhes bibliográficos
Main Authors: Mishra, Santosh K., Hoon, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670709/
https://ncbi.nlm.nih.gov/pubmed/23704570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1233765
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