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Selective Roles for Toll-Like Receptors 2, 4 and 9 in the Systemic Inflammation and Immune Dysfunction Following Peripheral Tissue Injury

BACKGROUND: Toll-like receptors (TLRs) detect endogenous ligands released after trauma and contribute to the proinflammatory response to injury. Post-traumatic mortality correlates with the extent of the immuno-inflammatory response to injury which is comprised of a complex regulation of innate and...

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Autori principali: Darwiche, Sophie S., Ruan, Xiangcai, Hoffman, Marcus K., Zettel, Kent R., Tracy, Aaron P., Schroeder, Linda M.I., Cai, Changchun, Hoffman, Rosemary A., Scott, Melanie J., Pape, Hans-Christoph, Billiar, Timothy R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670589/
https://ncbi.nlm.nih.gov/pubmed/23694872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e3182905ed2
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