Rare BRAF mutations in melanoma patients: implications for molecular testing in clinical practice

BACKGROUND: The detection of V600E BRAF mutation in melanoma is fundamental since here BRAF inhibitors represent an effective treatment. Non-V600E BRAF mutations that may also respond are not detected by certain screening methods. Thus, knowledge about detection of these mutations is needed. METHODS...

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Main Authors: Heinzerling, L, Kühnapfel, S, Meckbach, D, Baiter, M, Kaempgen, E, Keikavoussi, P, Schuler, G, Agaimy, A, Bauer, J, Hartmann, A, Kiesewetter, F, Schneider-Stock, R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Genetics and Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670489/
https://ncbi.nlm.nih.gov/pubmed/23579220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.143
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