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Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution
To what extent are evolutionary outcomes determined by a population's recent environment, and to what extent do they depend on historical contingency and random chance? Here we apply a unique experimental system to investigate evolutionary reproducibility and path dependence at the protein leve...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670371/ https://ncbi.nlm.nih.gov/pubmed/23674678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220670110 |
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