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A population-based experimental model for protein evolution: effects of mutation rate and selection stringency on evolutionary outcomes
Protein evolution is a critical component of organismal evolution and a valuable method for the generation of useful molecules in the laboratory. Few studies, however, have experimentally characterized how fundamental parameters influence protein evolution outcomes over long evolutionary trajectorie...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641671/ https://ncbi.nlm.nih.gov/pubmed/23360105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3016185 |
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