Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface

Estrogen receptor alpha (ERα) is involved in numerous physiological and pathological processes, including breast cancer. Breast cancer therapy is therefore currently directed at inhibiting the transcriptional potency of ERα, either by blocking estrogen production through aromatase inhibitors or anti...

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Detalhes bibliográficos
Main Authors: De Vries-van Leeuwen, Ingrid J., da Costa Pereira, Daniel, Flach, Koen D., Piersma, Sander R., Haase, Christian, Bier, David, Yalcin, Zeliha, Michalides, Rob, Feenstra, K. Anton, Jiménez, Connie R., de Greef, Tom F. A., Brunsveld, Luc, Ottmann, Christian, Zwart, Wilbert, de Boer, Albertus H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670367/
https://ncbi.nlm.nih.gov/pubmed/23676274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220809110
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