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Transformation of polarized epithelial cells by apical mistrafficking of epiregulin

Establishment and maintenance of apico-basolateral trafficking pathways are critical to epithelial homeostasis. Loss of polarity and trafficking fidelity are thought to occur as a consequence of transformation; however, here we report that selective mistrafficking of the epidermal growth factor rece...

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Detalhes bibliográficos
Main Authors: Singh, Bhuminder, Bogatcheva, Galina, Washington, Mary Kay, Coffey, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670353/
https://ncbi.nlm.nih.gov/pubmed/23671122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305508110
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