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Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction
Huntington disease is a progressive and fatal genetic disorder with debilitating motor and cognitive defects. Chorea, rigidity, dystonia, and muscle weakness are characteristic motor defects of the disease that are commonly attributed to central neurodegeneration. However, no previous study has exam...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670332/ https://ncbi.nlm.nih.gov/pubmed/23671115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220068110 |
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