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Huntington disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction

Huntington disease is a progressive and fatal genetic disorder with debilitating motor and cognitive defects. Chorea, rigidity, dystonia, and muscle weakness are characteristic motor defects of the disease that are commonly attributed to central neurodegeneration. However, no previous study has exam...

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Detalhes bibliográficos
Main Authors: Waters, Christopher W., Varuzhanyan, Grigor, Talmadge, Robert J., Voss, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670332/
https://ncbi.nlm.nih.gov/pubmed/23671115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220068110
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