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Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes

Natural genetic variation is a rich resource for identifying novel elements of cellular pathways such as endoplasmic reticulum (ER) stress. ER stress occurs when misfolded proteins accumulate in the ER and cells respond with the conserved unfolded protein response (UPR), which includes large-scale g...

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Detalhes bibliográficos
Main Authors: Chow, Clement Y., Wolfner, Mariana F., Clark, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670321/
https://ncbi.nlm.nih.gov/pubmed/23667151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307125110
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