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STAT3 inhibitors for cancer therapy: Have all roads been explored?

The signal transducer and activator of transcription STAT3 is a transcription factor which plays a key role in normal cell growth and is constitutively activated in about 70% of solid and hematological cancers. Activated STAT3 is phosphorylated on tyrosine and forms a dimer through phosphotyrosine/s...

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Detalles Bibliográficos
Main Authors: Fagard, Remi, Metelev, Valeri, Souissi, Inès, Baran-Marszak, Fanny
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670264/
https://ncbi.nlm.nih.gov/pubmed/24058788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.22882
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