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STAT3 inhibitors for cancer therapy: Have all roads been explored?
The signal transducer and activator of transcription STAT3 is a transcription factor which plays a key role in normal cell growth and is constitutively activated in about 70% of solid and hematological cancers. Activated STAT3 is phosphorylated on tyrosine and forms a dimer through phosphotyrosine/s...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670264/ https://ncbi.nlm.nih.gov/pubmed/24058788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.22882 |
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