Methylated trivalent arsenicals are potent inhibitors of glucose stimulated insulin secretion by murine pancreatic islets

Epidemiologic evidence has linked chronic exposure to inorganic arsenic (iAs) with an increased prevalence of diabetes mellitus. Laboratory studies have identified several mechanisms by which iAs can impair glucose homeostasis. We have previously shown that micromolar concentrations of arsenite (iAs...

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Main Authors: Douillet, Christelle, Currier, Jenna, Saunders, Jesse, Bodnar, Wanda M., Matoušek, Tomáš, Stýblo, Miroslav
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670188/
https://ncbi.nlm.nih.gov/pubmed/23261974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.12.007
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