Fatty Acid-Induced Production of Plasminogen Activator Inhibitor-1 by Adipose Macrophages Is Greater in Middle-Aged Versus Younger Adult Participants

BACKGROUND. Human aging is associated with heightened risk of diabetes and cardiovascular disease. Increased fat mass may contribute to age-related diseases by harboring inflammatory macrophages that produce metabolically important proteins such as plasminogen activator inhibitor-1 (PAI-1). Elevated...

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Main Authors: Esterson, Yonah B., Kishore, Preeti, Koppaka, Sudha, Li, Weijie, Zhang, Kehao, Tonelli, Julia, Lee, Do-Eun, Kehlenbrink, Sylvia, Lawrence, Stephanie, Crandall, Jill, Barzilai, Nir, Hawkins, Meredith
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670154/
https://ncbi.nlm.nih.gov/pubmed/23089338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gls200
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