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Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions
Cytoplasmic dynein plays important roles in mitosis and the intracellular transport of organelles, proteins, and mRNAs. Dynein function is particularly critical for survival of neurons, as mutations in dynein are linked to neurodegenerative diseases. Dynein function is also implicated in neuronal re...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3670090/ https://ncbi.nlm.nih.gov/pubmed/23475693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21102 |
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