Dependence of liver-specific transcription on tissue organization.

When the liver is disaggregated and hepatocytes are cultured as a cellular monolayer for 24 h, a sharp decline (80 to 99% decrease) in the transcription of most liver-specific mRNAs, but not common mRNAs, occurs (Clayton and Darnell, Mol. Cell. Biol. 2:1552-1561, 1983). A wide variety of culture con...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Clayton, D F, Harrelson, A L, Darnell, J E
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3841792/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.10.2623
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