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Altered cholesterol homeostasis in aged macrophages linked to neovascular macular degeneration
Abnormal lipid metabolism has been linked to age-related macular degeneration (AMD); choroidal neovascularization in late AMD commonly causes blindness. Sene et al. now demonstrate that in aged macrophages decreased ABCA1 expression, regulated by liver X receptor and miR-33, impairs export of intrac...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3669899/ https://ncbi.nlm.nih.gov/pubmed/23562072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.03.010 |
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