Amplification of the gene for histidyl-tRNA synthetase in histidinol-resistant Chinese hamster ovary cells.
Histidinol-resistant (HisOHR) mutants with up to a 30-fold increase in histidyl-tRNA synthetase activity have been isolated by stepwise adaptation of wild-type Chinese hamster ovary (CHO) cells to increasing amounts of histidinol in the medium. Immunoprecipitation of [35S]methionine-labeled cell lys...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1985
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2874482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.9.2381-2388.1985 |
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