Endothelial Nitric Oxide Synthase Reduces Crescentic and Necrotic Glomerular Lesions, Reactive Oxygen Production, and MCP1 Production in Murine Lupus Nephritis

Systemic lupus erythematosus, in both animal models and in humans, is characterized by autoantibody production followed by immune complex deposition in target tissues. Ensuing target organ damage is modulated by reactive intermediates, including reactive nitrogen and oxygen species, through as of no...

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Hauptverfasser: Gilkeson, Gary S., Mashmoushi, Ahmad K., Ruiz, Phillip, Caza, Tiffany N., Perl, Andras, Oates, Jim C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669382/
https://ncbi.nlm.nih.gov/pubmed/23741359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064650
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