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Interferon-α Negatively Regulates the Expression of Endothelial Nitric Oxide Synthase and Nitric Oxide Production: Implications for SLE

Systemic lupus erythematosus (SLE) is a known risk factor for endothelial dysfunction. Murine and human lupus studies have implicated a role for IFNα in vascular abnormalities associated with impaired blood vessel dilation. However, the impact of IFNα on mediators that induce vasodilation and modula...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Buie, Joy Jones, Renaud, Ludivine L, Muise-Helmericks, Robin, Oates, Jim C
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587385/
https://ncbi.nlm.nih.gov/pubmed/28779021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600108
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