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Apolipoprotein A-I glycation by Glucose and Reactive Aldehydes Alters Phospholipid Affinity but Not Cholesterol Export from Lipid-Laden Macrophages

Increased protein glycation in people with diabetes may promote atherosclerosis. This study examined the effects of non-enzymatic glycation on the association of lipid-free apolipoproteinA-I (apoA-I) with phospholipid, and cholesterol efflux from lipid-loaded macrophages to lipid-free and lipid-asso...

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Autori principali: Brown, Bronwyn E., Nobecourt, Estelle, Zeng, Jingmin, Jenkins, Alicia J., Rye, Kerry-Anne, Davies, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669297/
https://ncbi.nlm.nih.gov/pubmed/23741493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065430
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