Improved Production Process for Native Outer Membrane Vesicle Vaccine against Neisseria meningitidis

An improved detergent-free process has been developed to produce vaccine based on native outer membrane vesicles (NOMV) against Neisseria meningitidis serogroup B. Performance was evaluated with the NonaMen vaccine concept, which provides broad coverage based on nine distinct PorA antigens. Scalable...

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Main Authors: van de Waterbeemd, Bas, Zomer, Gijsbert, Kaaijk, Patricia, Ruiterkamp, Nicole, Wijffels, René H., van den Dobbelsteen, Germie P. J. M., van der Pol, Leo A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669287/
https://ncbi.nlm.nih.gov/pubmed/23741478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065157
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