Improved Production Process for Native Outer Membrane Vesicle Vaccine against Neisseria meningitidis

An improved detergent-free process has been developed to produce vaccine based on native outer membrane vesicles (NOMV) against Neisseria meningitidis serogroup B. Performance was evaluated with the NonaMen vaccine concept, which provides broad coverage based on nine distinct PorA antigens. Scalable...

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Autori principali: van de Waterbeemd, Bas, Zomer, Gijsbert, Kaaijk, Patricia, Ruiterkamp, Nicole, Wijffels, René H., van den Dobbelsteen, Germie P. J. M., van der Pol, Leo A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669287/
https://ncbi.nlm.nih.gov/pubmed/23741478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065157
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