Improved Production Process for Native Outer Membrane Vesicle Vaccine against Neisseria meningitidis

An improved detergent-free process has been developed to produce vaccine based on native outer membrane vesicles (NOMV) against Neisseria meningitidis serogroup B. Performance was evaluated with the NonaMen vaccine concept, which provides broad coverage based on nine distinct PorA antigens. Scalable...

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Autores principales: van de Waterbeemd, Bas, Zomer, Gijsbert, Kaaijk, Patricia, Ruiterkamp, Nicole, Wijffels, René H., van den Dobbelsteen, Germie P. J. M., van der Pol, Leo A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669287/
https://ncbi.nlm.nih.gov/pubmed/23741478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065157
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