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Dual suppressive effect of MTORC1 on autophagy: Tame the dragon by shackling both the head and the tail

The lysosome is a key subcellular organelle that receives and degrades macromolecules from endocytic, secretory and autophagic pathways. Lysosomal function is thus critical for an efficient autophagic process. However, the molecular mechanisms mediating lysosomal function upon autophagic induction a...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Jing, Tan, Shi-Hao, Codogno, Patrice, Shen, Han-Ming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669196/
https://ncbi.nlm.nih.gov/pubmed/23439250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23965
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