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Tumor suppressor gene PDCD4 negatively regulates autophagy by inhibiting the expression of autophagy-related gene ATG5

PDCD4 (programmed cell death protein 4), a suppressor of gene transcription and translation, plays a crucial inhibitory role in several types of human tumors. However, its underlying mechanisms remain unclear. Autophagy, an evolutionarily conserved catabolic process, maintains cellular homeostasis u...

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Detalhes bibliográficos
Main Authors: Song, Xingguo, Zhang, Xia, Wang, Xiaoyan, Zhu, Faliang, Guo, Chun, Wang, Qun, Shi, Yongyu, Wang, Jianing, Chen, Youhai, Zhang, Lining
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669183/
https://ncbi.nlm.nih.gov/pubmed/23486359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24069
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