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Deregulation of c-myc gene expression in human colon carcinoma is not accompanied by amplification or rearrangement of the gene.

The structure and expression of the c-myc oncogene were examined in 29 primary human colon adenocarcinomas. Dot blot hybridization of total RNA showed that 21 tumors (72%) had considerably elevated expression of c-myc (5- to 40-fold) relative to normal colonic mucosa. These data were corroborated by...

詳細記述

保存先:
書誌詳細
主要な著者: Erisman, M D, Rothberg, P G, Diehl, R E, Morse, C C, Spandorfer, J M, Astrin, S M
フォーマット: Artigo
言語:Inglês
出版事項: 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC366914/
https://ncbi.nlm.nih.gov/pubmed/3837853
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