Suppression of deregulated c-MYC expression in human colon carcinoma cells by chromosome 5 transfer.
Two-thirds of sporadic colon carcinomas express elevated levels of the c-MYC protooncogene. In addition, most colon carcinoma cell lines show constitutive elevated expression (10- to 40-fold over normal) of MYC RNA and protein that is not modulated in response to a mitogenic stimulus. Indirect immun...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741403/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.4.1482 |
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