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An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform

The proper identification of differentially methylated CpGs is central in most epigenetic studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA methylation; nevertheless, the design of an appropriate analysis pipeline faces severe challenges due to the convolution of biol...

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Detalhes bibliográficos
Main Authors: Marabita, Francesco, Almgren, Malin, Lindholm, Maléne E., Ruhrmann, Sabrina, Fagerström-Billai, Fredrik, Jagodic, Maja, Sundberg, Carl J., Ekström, Tomas J., Teschendorff, Andrew E., Tegnér, Jesper, Gomez-Cabrero, David
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669124/
https://ncbi.nlm.nih.gov/pubmed/23422812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24008
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