An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform

The proper identification of differentially methylated CpGs is central in most epigenetic studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA methylation; nevertheless, the design of an appropriate analysis pipeline faces severe challenges due to the convolution of biol...

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Main Authors: Marabita, Francesco, Almgren, Malin, Lindholm, Maléne E., Ruhrmann, Sabrina, Fagerström-Billai, Fredrik, Jagodic, Maja, Sundberg, Carl J., Ekström, Tomas J., Teschendorff, Andrew E., Tegnér, Jesper, Gomez-Cabrero, David
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669124/
https://ncbi.nlm.nih.gov/pubmed/23422812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24008
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