Novel alterations in the epigenetic signature of MeCP2-targeted promoters in lymphocytes of Rett syndrome patients

Rett syndrome (RTT) is a neurodevelopmental disorder with neurological symptoms, such as motor disorders and mental retardation. In most cases, RTT is caused by mutations in the DNA binding protein MeCP2. In mice, MeCP2 gene deletion has been reported to result in genome-wide increased histone acety...

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Detalhes bibliográficos
Main Authors: Lilja, Tobias, Wallenborg, Karolina, Björkman, Karin, Albåge, Margareta, Eriksson, Maud, Lagercrantz, Hugo, Rohdin, Malin, Hermanson, Ola
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669117/
https://ncbi.nlm.nih.gov/pubmed/23348913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.23752
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