Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden

Over 80% of women diagnosed with advanced-stage ovarian cancer die as a result of disease recurrence due to failure of chemotherapy treatment. In this study, using two distinct ovarian cancer cell lines (epithelial OVCA 433 and mesenchymal HEY) we demonstrate enrichment in a population of cells with...

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Detalhes bibliográficos
Main Authors: Abubaker, Khalid, Latifi, Ardian, Luwor, Rod, Nazaretian, Simon, Zhu, Hongjian, Quinn, Michael A, Thompson, Erik W, Findlay, Jock K, Ahmed, Nuzhat
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668985/
https://ncbi.nlm.nih.gov/pubmed/23537295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-24
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