Multicolor microRNA FISH effectively differentiates tumor types

MicroRNAs (miRNAs) are excellent tumor biomarkers because of their cell-type specificity and abundance. However, many miRNA detection methods, such as real-time PCR, obliterate valuable visuospatial information in tissue samples. To enable miRNA visualization in formalin-fixed paraffin-embedded (FFP...

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Detalhes bibliográficos
Main Authors: Renwick, Neil, Cekan, Pavol, Masry, Paul A., McGeary, Sean E., Miller, Jason B., Hafner, Markus, Li, Zhen, Mihailovic, Aleksandra, Morozov, Pavel, Brown, Miguel, Gogakos, Tasos, Mobin, Mehrpouya B., Snorrason, Einar L., Feilotter, Harriet E., Zhang, Xiao, Perlis, Clifford S., Wu, Hong, Suárez-Fariñas, Mayte, Feng, Huichen, Shuda, Masahiro, Moore, Patrick S., Tron, Victor A., Chang, Yuan, Tuschl, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668843/
https://ncbi.nlm.nih.gov/pubmed/23728175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68760
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