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Cysteine Proteinase from Streptococcus pyogenes Enables Evasion of Innate Immunity via Degradation of Complement Factors

Streptococcus pyogenes is an important human pathogen that causes invasive diseases such as necrotizing fasciitis, sepsis, and streptococcal toxic shock syndrome. We investigated the function of a major cysteine protease from S. pyogenes that affects the amount of C1-esterase inhibitor (C1-INH) and...

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Huvudupphovsmän: Honda-Ogawa, Mariko, Ogawa, Taiji, Terao, Yutaka, Sumitomo, Tomoko, Nakata, Masanobu, Ikebe, Kazunori, Maeda, Yoshinobu, Kawabata, Shigetada
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668742/
https://ncbi.nlm.nih.gov/pubmed/23589297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469106
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