Cysteine Proteinase from Streptococcus pyogenes Enables Evasion of Innate Immunity via Degradation of Complement Factors

Streptococcus pyogenes is an important human pathogen that causes invasive diseases such as necrotizing fasciitis, sepsis, and streptococcal toxic shock syndrome. We investigated the function of a major cysteine protease from S. pyogenes that affects the amount of C1-esterase inhibitor (C1-INH) and...

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Bibliografische gegevens
Hoofdauteurs: Honda-Ogawa, Mariko, Ogawa, Taiji, Terao, Yutaka, Sumitomo, Tomoko, Nakata, Masanobu, Ikebe, Kazunori, Maeda, Yoshinobu, Kawabata, Shigetada
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668742/
https://ncbi.nlm.nih.gov/pubmed/23589297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469106
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