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Group A Streptococcal Cysteine Protease Cleaves Epithelial Junctions and Contributes to Bacterial Translocation

Group A Streptococcus (GAS) is an important human pathogen that possesses an ability to translocate across the epithelial barrier. In this study, culture supernatants of tested GAS strains showed proteolytic activity against human occludin and E-cadherin. Utilizing various types of protease inhibito...

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Detalhes bibliográficos
Main Authors: Sumitomo, Tomoko, Nakata, Masanobu, Higashino, Miharu, Terao, Yutaka, Kawabata, Shigetada
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650370/
https://ncbi.nlm.nih.gov/pubmed/23532847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.459875
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