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Group A Streptococcal Cysteine Protease Cleaves Epithelial Junctions and Contributes to Bacterial Translocation

Group A Streptococcus (GAS) is an important human pathogen that possesses an ability to translocate across the epithelial barrier. In this study, culture supernatants of tested GAS strains showed proteolytic activity against human occludin and E-cadherin. Utilizing various types of protease inhibito...

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Bibliografische gegevens
Hoofdauteurs: Sumitomo, Tomoko, Nakata, Masanobu, Higashino, Miharu, Terao, Yutaka, Kawabata, Shigetada
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650370/
https://ncbi.nlm.nih.gov/pubmed/23532847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.459875
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