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Control of Myofibroblast Differentiation by Microtubule Dynamics through a Regulated Localization of mDia2

Myofibroblast differentiation plays a critical role in wound healing and in the pathogenesis of fibrosis. We have previously shown that myofibroblast differentiation is mediated by the activity of serum response factor (SRF), which is tightly controlled by the actin polymerization state. In this stu...

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Autori principali: Sandbo, Nathan, Ngam, Caitlyn, Torr, Elizabeth, Kregel, Steve, Kach, Jacob, Dulin, Nickolai
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668708/
https://ncbi.nlm.nih.gov/pubmed/23580645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464461
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